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New HIV jabs taken two months apart hailed as huge step forward
Safe injectable antiretroviral drugs, approved by health bodies, ‘could lift burden of daily oral therapy’
Thousands of people living with HIV in Britain are to be freed from the burden of taking daily pills, after health chiefs gave the green light for a revolutionary treatment by injection every two months.
Draft guidance from the National Institute for Health and Care Excellence (Nice) recommends offering the antiretroviral drugs cabotegravir and rilpivirine in England and Wales after trials proved they work as effectively as daily tablets.
The Scottish Medicines Consortium has also approved the injections for adults living with HIV in Scotland.
Although HIV, which attacks the immune system, is still incurable, researchers found that patients who had the new treatment could reach a point where the virus particles in their blood (the viral load) were so low those particles could not be detected or transmitted between people.
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The treatment is the first long-acting, injectable treatment for adults with HIV. It is also the first recommendation Nice has made about the use of HIV treatments since they came under its remit two years ago.
Cabotegravir with rilpivirine is now being recommended as an option for adults with HIV infection when antiretroviral medicines they are already taking have kept the virus at a low level, and where there is no evidence to suspect viral resistance and no previous failure of other antiHIV medicines.
About 100,000 people have HIV in Britain. It is estimated that initially at least 13,000 people will be eligible for the new jab in England alone.
At present treatment for HIV involves life-long antiretroviral regimens taken as tablets every day. Clinical trial results show cabotegravir with rilpivirine is as effective as oral drugs at keeping the viral load low. The antiretrovirals are administered as two separate injections every two months. (…)
A treatment only required six times a year will make taking medicine easier for some people, and is more discreet for those who feel unable to be open about their HIV status. Experts say removing the need to take pills every single day may also lessen the emotional toll of living with HIV, and improve the numbers of people who adhere to their treatment regime.
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Source:https://www.theguardian.com/society/2021/nov/18/new-hivjabs-taken-two-months-apart-hailed-as-huge-step-forward. Access: 11/22/2021.
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